Survival and long-term outcomes after mitral valve replacement in patients aged 18 to 50 years
Samuel R. Schnittman, MD, David H. Adams, MD, Shinobu Itagaki, MD, Nana Toyoda, MD, Natalia N. Egorova, PhD, Joanna Chikwe, MD
OBJECTIVE:
To provide long-term data on survival and major morbidity after mitral valve replacement in patients aged 18 to 50 years.
METHODS:
Retrospective analysis of 2727 patients aged 18 to 50 years who underwent isolated mitral replacement in California and New York from 1997 to 2006. Median follow-up time was 12.4 years (maximum 15.0 years). The primary endpoint was mortality; secondary endopoints were stroke, major bleeding, and reoperation. Propensity matching yielded 373 patient pairs.
CONCLUSIONS:
The significant survival benefit associated with mechanical mitral valve replacement in adults ≤50 years may be due to the practice of implanting bioprostheses in sicker patients or those judged less likely to comply with long-term medication despite adjustment for baseline characteristics in propensity score matching.
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Publications
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Serratus Anterior Plane Block for Transapical Off-Pump Mitral Valve Repair With NeoChord Implantation.
Himani V. Bhatt, DO, Morgan L. Montgomery, MD, Alexander J.C. Mittnacht, MD, Ali Shariat, MD, Ahmed El-Eshmawi, MD, David H. Adams, MD, Menachem M. Weiner, MD -
Mitral valve repair for severe mitral valve regurgitation during left ventricular assist device implantation.
Amit Pawale, MD, Shinobu Itagaki, MD, Aditya Parikh, MD, Sean P. Pinney, MD, David H.Adams, MD, Anelechi C. Anyanwu, MD -
Reply: Off-Pump Surgeons' Experience Is Paramount to Delivering High-Quality CABG Outcomes: But What Constitutes Experience?
Joanna Chikwe, MD, Timothy Lee, MD, Shinobu Itagaki, MD, David H. Adams, MD, Natalia N. Egorova, PhD -
Correlation of 2-Dimensional and 3-Dimensional Echocardiographic Analysis to Surgical Measurements of the Tricuspid Valve Annular Diameter.
Himani V. Bhatt, DO, MPA, FASE, FASA, John Spivack, PhD, Pritul R. Patel, MD, Ahmed El-Eshmawi, MD, Yasmin Amir, BS, David H. Adams, MD, Gregory W. Fischer, MD, FASA