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Dimosthenis Pandis, MD, Partho P. Sengupta, MD, Javier Castillo, MD, Guiseppe Caracciolo, MD, PhD, Gregory W. Fischer, MD, Jagat Narula, MD, PhD, Anelechi C. Anyanwu, MD, and David H. Adams, MD

The optimal timing of mitral valve repair (MVr) in patients with chronic severe degenerative mitral regurgitation (MR) remains controversial and is broadly based on either measurable loss of systolic function, as determined by left ventricular (LV) ejection fraction (LVEF) and/or LV chamber remodeling. The aim of this study was to test the hypothesis that the assessment of LV deformation by speckle-tracking echocardiography might uncover subclinical changes for predicting reduction of LVEF after MVr.

Page Created: December 19, 2017 Last Updated: January 03, 2018

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